Bow Wow has made guest appearances on Brandy's TV sitcom, Moesha, as well as The Steve Harvey Show and Brothers Garcia. He made his acting debut in the film Like Mike which was released on July 3, 2002, in which he starred as a young orphan who gets a shot at playing in the NBA. Before Like Mike he made cameos in All About The Benjamins and "Carmen: A Hip Hopera". Bow Wow also co-starred with Cedric the Entertainer, Vanessa L. Williams, and Solange Knowles in Johnson Family Vacation. Since the success of Like Mike, Bow Wow has starred in several Hollywood films, including Roll Bounce, The Fast and the Furious: Tokyo Drift and Hurricane Season.
He has also made guest appearances on Smallville and Ugly Betty. He was part of the cast of the fifth season of HBO's Entourage, playing Charlie an up-and-coming comedian, and Eric Murphy's newest client. He starred in a 2010 comedy film, Lottery Ticket, with Ice Cube. He is working on a documentary on his life entitled Who Is Shad Moss?; Bow Wow stated that the documentary goes all the way back when he was on Death Row Records and it was released in 2011. Bow Wow starred in the film version of Madea's Big Happy Family, released in April 2011. In August 2014, Bow Wow announced that he would star in an upcoming CSI spinoff entitled CSI: Cyber.
His family supported him through his choice of music as a career. Bow Wow now lives in Atlanta, Georgia, along with his mother, who previously owned a clothing store in the Atlantic Station area of Atlanta, named "Taste". On July 7, 2011, Bow Wow revealed that he has a child, and had kept it a secret to keep this part of his life private. Bow Wow is currently engaged to TV Personality and Urban Model, Erica Mena.